The UC Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND) is internationally recognized for its research accomplishments in disorders of the brain, particularly those that are age-related. UCI MIND is the University’s center for aging and dementia research, with our faculty seeking to understand the causes leading to neurological disorders such as Alzheimer’s disease, frontotemporal dementia, Lewy body dementia, and Huntington’s disease.

For those suffering from age-related memory problems, our goal is to develop improved means for effective diagnosis and treatment and to provide help to families and caregivers. UCI MIND is home to one of 29 Alzheimer’s Disease Research Centers funded by the National Institute on Aging and is also one of 10 California Alzheimer’s Disease Centers.


UCI MIND seeks to enhance the quality of life for older adults by researching genetic, clinical, and lifestyle factors that promote successful brain aging. Toward this end, UCI MIND facilitates and coordinates a number of activities, some of which are listed below:

  • Conduct longitudinal research that follows individuals with and without cognitive impairment to evaluate their clinical and neuropsychological changes over time.
  • Perform clinical trials of promising investigational therapeutics.
  • Share biological resources such as human brain tissue, serum, DNA, and cerebrospinal fluid from well-characterized clinical subjects with researchers worldwide.
  • Deliver community outreach with the goal of increasing participation in research.
  • Train and educate the next generation of graduate students and postdoctoral fellows in the field of brain aging and neurodegeneration.
  • Stimulate research through individual and collaborative grants and philanthropic fundraising.
  • Sponsor seminars and meetings to promote scholarship and information exchange.
  • Partner with community-based organizations serving individuals with Alzheimer’s disease and related dementias to educate and raise awareness among the community.


UCI MIND is at the forefront of Alzheimer’s disease research. For more than 30 years, UCI researchers have worked toward understanding the causes and risk factors associated with Alzheimer’s disease and other dementias, always with an eye toward effective treatment and prevention. Some research opportunities include:

  • Longitudinal studies
  • Studies of successful aging
  • Clinical trials
  • Brain imaging studies